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       SEMINAR OF THE LABORATORY FOR COMPUTER DESIGN OF MATERIALS
        Institute for Computational Sciences and Informatics
  CSI 929  (http://science.gmu.edu/physics/seminar/schedule.html)
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     Immobilization and Patterning of Biomaterials on Surfaces:
          Preparation, Characterization and Applications

		           David Turner
       Laboratory for Molecular Interfacial Interactions
           Naval Research Laboratory, Washington D.C.

    In this seminar I will discuss some of the approaches available
for immobilization and patterning of biomaterials on solid surfaces,
characterization methods, and applications of patterned biomaterials. 
Selective physisorption and chemisorption of proteins to chemically
patterned surfaces will be described in light of associated  problems
due to non-specific adsorption.  Patterning of microtubules is given 
an example of patterning by selective adhesion to chemically modified
surfaces.  Novel approaches for biomaterial patterning, such as
enzyme-based patterning and pattern stamping, will also be described
and compared with conventional photolithographic patterning methods. 
Finally, the application of these principals to biosensor development 
will be evaluated.

                          Monday , April 8 1996
                                  5:00 pm
                          Room 206, Science & Tech. I
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