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                SEMINAR OF THE DYNAMICAL SYSTEMS GROUP
        Institute for Computational Sciences and Informatics
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         Assembling the Molecular Machine Shop--Steps Towards 
   Chemical and Spatial Surface Modification at the Molecular Level

                        Bruce Paul Gaber
         Laboratory for Molecular Interfacial Interactions
             Naval Research Laboratory, Washington D.C.


I propose that it is possible to pattern a surface with near-molecular 
precision using as machine tool the atomic force microscope (AFM).  In 
particular, I suggest that AFM tips modified with active enzymes can be 
used as "tool bits" to bring about highly specific chemical modifications 
on monomolecular surfaces of biomolecules.  I will discuss our progress 
towards assembling a "Molecular Machine Shop" capable of achieving this 
goal.

		      Monday , March 27, 1995
			        5:30 pm
		      Room 206, Science & Tech. I
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